[HTML][HTML] Allostery in the nitric oxide dioxygenase mechanism of flavohemoglobin
AM Gardner, PR Gardner - Journal of Biological Chemistry, 2021 - ASBMB
… activate the NO dioxygenase function of Escherichia coli flavohemoglobin. Steady-state and
… E and F-helices and switches an electron transfer gate formed by LysF7, GlnE7, and water. …
… E and F-helices and switches an electron transfer gate formed by LysF7, GlnE7, and water. …
Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network of Escherichia coli
JL Robinson, MP Brynildsen - Proceedings of the National …, 2016 - National Acad Sciences
… of Escherichia coli nitric-oxide dioxygenase (flavohemoglobin). The B10 tyrosine
hydroxyl is essential for dioxygen binding and catalysis. J Biol Chem 275, 12581–12589 (2000). …
hydroxyl is essential for dioxygen binding and catalysis. J Biol Chem 275, 12581–12589 (2000). …
[HTML][HTML] Flavohaemoglobin: The pre-eminent nitric oxide–detoxifying machine of microorganisms
RK Poole - F1000Research, 2020 - ncbi.nlm.nih.gov
… It is soluble in water (approximately 1.6 mM at 37 C and 1.94 … to the NO dioxygenase
activities of flavohaemoglobin 12 . … Thus, for example, the Escherichia coli flavohaemoglobin (…
activities of flavohaemoglobin 12 . … Thus, for example, the Escherichia coli flavohaemoglobin (…
[HTML][HTML] A nitric oxide synthase–like protein from Synechococcus produces NO/NO3− from l-arginine and NAPDH in a tetrahydrobiopterin-and Ca2+-dependent …
AL Picciano, BR Crane - Journal of Biological Chemistry, 2019 - ASBMB
… Escherichia coli strains against nitrosative stress, even in a mutant devoid of NO-protective
flavohemoglobin… NOS and NO oxygenase activities, requires H 4 B, and may play a role in Ca …
flavohemoglobin… NOS and NO oxygenase activities, requires H 4 B, and may play a role in Ca …
Dioxygen and glucose force motion of the electron-transfer switch in the iron (III) flavohemoglobin-type nitric oxide dioxygenase
AM Gardner, PR Gardner - Journal of Inorganic Biochemistry, 2023 - Elsevier
… of the Escherichia coli flavoHb-NOD [8,9]. However, in the resting state, the Fe(III)-flavoHb
binds … and the bound ‘Coulomb blockade’ water molecule poised between the FAD C8M and …
binds … and the bound ‘Coulomb blockade’ water molecule poised between the FAD C8M and …
Ordered Motions in the Nitric-Oxide Dioxygenase Mechanism of Flavohemoglobin and Assorted Globins with Tightly Coupled Reductases
PR Gardner - Protein Reviews: Volume 23, 2022 - Springer
… -detoxifying NO metabolic activity with the flavoHb in Escherichia coli (Gardner et al. 1998a;
… modeled on the E. coli ferric flavoHb with a bridging Coulomb blockade water molecule (W) …
… modeled on the E. coli ferric flavoHb with a bridging Coulomb blockade water molecule (W) …
Nitric oxide-mediated induction of dispersal in Pseudomonas aeruginosa biofilms is inhibited by flavohemoglobin production and is enhanced by imidazole
… the NO dioxygenase activity of flavohemoglobin, attenuated … is capable of sensing NO in
Escherichia coli (39). The NO-… prepared in Milli-Q water at different concentrations. Biofilms …
Escherichia coli (39). The NO-… prepared in Milli-Q water at different concentrations. Biofilms …
Distinct nitrite and nitric oxide physiologies in Escherichia coli and Shewanella oneidensis
Q Meng, J Yin, M Jin, H Gao - Applied and Environmental …, 2018 - Am Soc Microbiol
… decompose NO include flavohemoglobin (Hmp) functioning as nitric-oxide dioxygenase (NOD), …
(such as flavin reductase Fre of Escherichia coli), and the hybrid cluster protein (Hcp) (13…
(such as flavin reductase Fre of Escherichia coli), and the hybrid cluster protein (Hcp) (13…
[HTML][HTML] A critical role for staphylococcal nitric oxide synthase in controlling flavohemoglobin toxicity
RM Singh, SS Chaudhari, S Panda, EH Hutfless… - Redox Biology, 2023 - Elsevier
… Under these conditions, growth can only resume once nitric oxide (NO) is detoxified by the
flavohemoglobin Hmp. Paradoxically, S. epidermidis produces endogenous NO through its …
flavohemoglobin Hmp. Paradoxically, S. epidermidis produces endogenous NO through its …
Resonance Raman studies on the flavohemoglobin of the protist Giardia intestinalis: evidence of a type I/II-peroxidase-like heme environment and roles of the active …
B Lukaszewicz, E McColl, J Yee, S Rafferty… - JBIC Journal of …, 2017 - Springer
… ], likely through water molecules [9], and two residues on helix E (… distal residue to the heme
iron in the flavohemoglobin of E. … it is relevant for the NO-dioxygenase reaction and it was not …
iron in the flavohemoglobin of E. … it is relevant for the NO-dioxygenase reaction and it was not …